About the job

Job summary

We are currently looking for a Principal Scientist to join our Diagnostics Team within the Science, Research & Innovation group, to work on an exciting project addressing the global challenge of anti-microbial resistance.

This is a full-time opportunity, on a fixed term contract basis until 31st March 2027. The role will be lab-based in South Mimms, Hertfordshire. Please be aware that this role can only be worked in the UK and not overseas.  

 

Who are we? 

 

The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research.  

 

The Science, Research and Innovation Group delivers public health impact, world-leading research innovation, and a unique regulatory proposition for patients and users via an ambitious Science Strategy which will balance innovation against sustainability and affordability. It is divided into 6 sub-Groups, Innovation Accelerator, Clinical Investigations and Trials, Research and Development, Standards Lifecycle, Control Testing and Quality Assurance and Health & Safety.

 

The Diagnostics Team in Research and Development undertake regulatory scientific research activities that guides the development of reference materials that are used to assess the analytical performance of complex diagnostic assays for infectious and neurodegenerative diseases, cancer genomics, and anti-microbial resistance.

 

What’s the role?

This is a new post, funded by DHSC GAMRIF, to establish and lead a small team developing physical and documentary standards that will guide innovators and regulators, and accelerate patient access to novel biologicals and diagnostics that address the global challenge of anti-microbial resistance.

Job description

-          Lead the team funded by DHSC GAMRIF, including the line management of two SEO Senior Scientists

 

-          Initiate and lead R&D projects that address key regulatory and scientific questions pertaining to novel AMR medicines and diagnostics, including securing external funding to establish and lead national and international collaborative work activities addressing the accelerated regulatory approval of novel and important medicines.

 

-          Establish and maintain relationships and collaborations with external stakeholders (including industry, academia, government departments, regulatory agencies and non-profit philanthropic organisations) as appropriate to identify and progress research priorities to deliver outputs that positively impact health of patients.

 

-          Provide expert scientific advice on the regulation and standardisation of assays and therapeutic products relating to the AMR to colleagues in the Agency and other Government departments as appropriate.

Person specification

Our successful candidate will have: 

 

-          A Ph.D. or equivalent with significant post-doctoral research experience and evidence of collaborative, multidisciplinary working.

 

-          Extensive experience in experimental design, biological standardisation, assay development

 

-          Experience of engaging with external stakeholders and partners to promote knowledge exchange and build productive relationships.

 

-          A good knowledge of, and practical experience in, a broad range of laboratory techniques used to assess and characterise biological molecules and biotherapeutics.

If you would like to find out more about this fantastic opportunity, please read our Job Description and Person Specification! 

 

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Benefits

Alongside your salary of £56,353, Medicines and Healthcare Products Regulatory Agency contributes £15,215 towards you being a member of the Civil Service Defined Benefit Pension scheme. Find out what benefits a Civil Service Pension provides.

Things you need to know

Selection process details

We use the Civil Service Success Profiles to assess our candidates, find out more here. 

• Online application form, including a statement of suitability, attached as a PDF of no more than 1000 words demonstrating how you meet the person specification. Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application. Please ensure not to include any personal identifying information on your supporting information.
• Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles. 

Applicants are assessed on whether they meet any mandatory requirements as well as the necessary skills and experience for the role. Applications are scored based on the statement of suitability provided. You can view the criteria for this role in the job description.

 

Use of AI in Job Applications

 

 

Applicants must ensure that anything submitted is factually accurate and truthful. Plagiarism can include presenting the ideas and experience of others, or generated by artificial intelligence, as your own.

 

 

If you require any disability related adjustments at any point during the process, please contact careers@mhra.gov.uk as soon as possible. 

  

Closing date: 17 July 2024

Shortlisting date: 18 July 2024

Interview date: 29 July 2024

 

Candidates will be contacted within a week of the sift and the interviews completed to inform them of the outcome.

 

If you need assistance applying for this role or have any other questions, please contact careers@mhra.gov.uk 

 

Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules. Further information on whether you are able to apply is available here. 

Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must complete basic personnel security standard checks.

Applicants who are successful at interview will be, as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicant’s details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government.

Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility here.

 

Successful candidates may be subject to annual Occupational Health reviews dependent on role requirements. If you have any queries, please contact careers@mhra.gov.uk.

 

In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should firstly contact Mira Mepa, Head of Recruitment and Operations, Mira.Mepa@mhra.gov.uk.  

 

If you are not satisfied with the response you receive, you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk 

 

info@csc.gov.uk 

Civil Service Commission 

Room G/8 

1 Horse Guards Road 

London 

SW1A 2HQ 

Feedback will only be provided if you attend an interview or assessment.

Security

Successful candidates must undergo a criminal record check. People working with government assets must complete baseline personnel security standard (opens in new window) checks.

Nationality requirements

This job is broadly open to the following groups:

• UK nationals
• nationals of the Republic of Ireland
• nationals of Commonwealth countries who have the right to work in the UK
• nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the European Union Settlement Scheme (EUSS) (opens in a new window)
• nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)
• individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020
• Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service

Further information on nationality requirements (opens in a new window)

Working for the Civil Service

The Civil Service Code (opens in a new window) sets out the standards of behaviour expected of civil servants.

We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's recruitment principles (opens in a new window). The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria. The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.